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Title of Article

MODIFICATION OF DROPERIDOL GANGLION-BLOCKING EFFECT BY HEPARIN


Issue
2
Date
 2010

Article type
 scientific article
UDC
612.57
Pages
611-617
Keywords
droperidol, heparin, superior cervical sympathetic ganglion


Authors
Butylin A.G.
Nizhegorodskiy gosuniversitet im. N.I. Lobachevskogo

Khomutov A.E.
Nizhegorodskiy gosuniversitet im. N.I. Lobachevskogo

Pursanov K.A.
Nizhegorodskaya gosudarstvennaya meditsinskaya akademiya


Abstract
The impact of exogenous and endogenous heparins on disorders of excitation conduction in the superior cervical sympathetic ganglion (SCSG) caused by droperidol has been examined in the experiments on cats. It has been shown that droperidol inhibits the excitation conduction in SCSG acting in the zone of both presynaptic and postsynaptic endings. Heparin reduces considerably the ganglion-blocking effect of droperidol.

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