Вестник Нижегородского университета им. Н.И. Лобачевского. Серия: Социальные науки

16+

Title of Article

SAFETY ASSESSMENT OF ALBUMIN PREPARATIONS MANUFACTURING WITH RESPECT TO PARVOVIRUS B19

Issue	1
Date	2012

Article type	scientific article	UDC	577.112.083
Pages	96-99	Keywords	albumin, plasma fractionation, viral safety, parvovirus B19, viral reduction

Authors

Filatova Ekaterina ViktorovnaFilial NPO «Mikrogen» Nizhegorodskoe predpriyatie po proizvodstvu bakteriynykh preparatov «ImBio»
Zubkova Nataliya VasilevnaFilial NPO «Mikrogen» Nizhegorodskoe predpriyatie po proizvodstvu bakteriynykh preparatov «ImBio»
Korotkova Tatyana VladimirovnaFilial NPO «Mikrogen» Nizhegorodskoe predpriyatie po proizvodstvu bakteriynykh preparatov «ImBio»
Galgovskaya Svetlana AlfredovnaFilial NPO «Mikrogen» Nizhegorodskoe predpriyatie po proizvodstvu bakteriynykh preparatov «ImBio»

Abstract

We have carried out model ethanol fractionation of plasma pools containing parvovirus B19 to determine viral DNA distribution over albumin manufacturing stages. The purpose of the study was to evaluate the efficacy of ethanol fractionation at additional stages for the removal/inactivation of parvovirus B19 during the manufacturing of albumin. The safety of albumin production technology has been confirmed by the results of the study of albumin preparations manufactured during 2008-2010.

File (in Russian)