During the period from 2002 to 2011, 1060 patients with various neuroinfections were surveyed by PCR method. The samples of liquor were investigated. A wide distribution of the traditional agents as well as Enterovirus, Neisseria meningitidis and Streptococcus pneumoniae was shown. In patients with meningitis, sufficiently high level of replication of the herpes group viruses was identified, the Epstein-Barr virus being detected most often. Some cases of meningitis caused by M. tuberculosis were identified. The high efficiency of the PCR detection of etiologic agents of various variants of neuroinfections (85%) was demonstrated. The data obtained indicate the usefulness of and the need for PCR examination of patients with neuroinfections with regard to the proposed range of infectious agents.
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