INFLUENCE OF ANGIOTENSIN-CONVERTING ENZYME INHIBITORS AND BETA-ADRENOBLOCKERS ON THE NEUROHORMONES’ LEVELS IN A HEART FAILURE MODEL IN RATS |
| 2 | |
| 2012 |
| scientific article | 616.127-085:615.357 | ||
| 230-235 |
| In experimental chronic heart failure beta-adrenoblockers had a more balanced effect on the neurohormonal systems as compared with the angiotensin-converting enzyme inhibitors. The efficacy of beta-adrenoblockers without intrinsic sympathomimetic activity was higher than that of pindolol, whereas lipophilic angiotensin-converting enzyme inhibitors were superior to the hydrophilic lisinopril. Combined treatment had an advantage over monotherapy in reducing sympathoadrenal activity only. |
 |