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Title of Article

THE INFLUENCE OF BETA-ADRENOBLOCKERS ON PLASMA LIPID SPECTRUM IN EXPERIMENTAL HEART FAILURE


Issue
2
Date
2012

Article type
scientific article
UDC
616.127-085:577.161.2.011
Pages
285-288
Keywords
 


Authors
Sidorov Aleksandr Vyacheslavovich
Yaroslavskaya gosudarstvennaya meditsinskaya akademiya

Salnikov Evgeniy Valentinovich
Yaroslavskaya gosudarstvennaya meditsinskaya akademiya


Abstract
The character of beta-adrenoblockers’ influence on blood lipid spectrum in heart failure depended on its selectivity for ? 1-adrenoreceptors. The most selective drugs nebivolol and metoprolol had a metabolic neutral profile of action, and nebivolol even decreased lipoproteins of very low density concentration. Less selective and especially nonselective beta-adrenoblockers pindolol and propranolol brought down high-density lipoproteins levels increasing atherogenic potential of plasma.

File (in Russian)