LOCALIZATION OF P53 PROTEIN IN CHROMATIN FRACTIONS AND NUCLEAR MATRICIES IN CELLS OF DIFFERENT TYPES |
| 3 | |
| 2011 |
| scientific article | 57.576.315.42 | ||
| 138-144 | nuclear matrix, chromatin fractionation, p53 |
| The tumor suppressor p53 can associate with the nuclear matrix. The fractionation of nuclei and purification of
nuclear matrix from cells of different types have been carried out and p53 protein content in fractions of the cell
nucleus has been studied. It is shown that localization of p53 in chromatin fractions and the degree of its association
with the nuclear matrix depend on the type of cells. |
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