КОНКУРЕНТНАЯ ДИНАМИКА И БИСТАБИЛЬНОСТЬ В ДВУХКОМПОНЕНТНОЙСИНТЕТИЧЕСКОЙ ГЕННОЙ СЕТИ |
4 | |
2014 |
научная статья | 530.182, 577.218, 537.86 | ||
456-463 | конкуренция, бистабильность, клетка, регуляторныесети, синтетическаябиология |
Предлагается схема двухкомпонентной синтетической генной сети, реализующей конкурентную динамику, и исследуется ее модель. Две части, составляющие полную сеть, разнесены между популяциями клеток и взаимно подавляют активность друг друга. Для сосредоточенной модели, описывающей локальную динамику, показана возможность бистабильности. В распределенной модели, описывающей пространственно-временную динамику среды, содержащей смесь клеток обеих популяций, показано существование фронтов - неподвижных в случае симметрии между конкурирующими компонентами либо распространяющихся при наличии асимметрии. |
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