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Title of Article

Chorionic gonadotropin action upon the Plisse lymphosarcoma growth and the number of CD4+mononuclear cells in the rat peripheral blood


Issue
1
Date
2008

Article type
scientific article
UDC
616-006
Pages
67-72
Keywords
 


Authors
Filatova E.N.
Nizhegorodskiy gosuniversitet im. N.I. Lobachevskogo

Aksenova T.V.
Nizhegorodskiy gosuniversitet im. N.I. Lobachevskogo

Khakhina Yu.Yu.
Nizhegorodskiy gosuniversitet im. N.I. Lobachevskogo

Novikov V.V.
Nizhegorodskiy gosuniversitet im. N.I. Lobachevskogo

Solopaeva I.M.
Nizhegorodskaya gosudarstvennaya meditsinskaya akademiya

Ivanova N.L.
Nizhegorodskaya gosudarstvennaya meditsinskaya akademiya


Abstract
The human chorionic gonadotropin belongs to the glycoprotein gonadotropin hormone family. It is produced in many mammal tissues and organs and is of primary importance in the processes of cell reproduction, growth and reparation. We have studied the human chorionic gonadotropin impact upon the Plisse lymphosarcoma genesis and the number of CD4+mononuclear cells in the blood of tumor carrying rats. As a result, a complex hormone action has been revealed that l eads to slowing down the tumor growth and correction of the tumor dependent immunodeficiency. We have also found a differently directed action of the human chorionic gonadotropin upon undifferentiated cells of Plisse lymphosarcoma and differentiated cells of normal body tissues.

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