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Title of Article

CRYSTALLOSTASIS PHYSIOLOGY AND PATHOLOGY: A GENERAL PARADIGM AND INVESTIGATION PROSPECTS


Issue
1
Date
2010

Article type
scientific article
UDC
577.1 : 612.015.347
Pages
135-139
Keywords
crystallostasis, crystal pathology, metabolism, biosystem, physiology, biocrystallization


Authors
Martusevich A.K.
Nizhegorodskiy nauchno-issledovatelskiy institut travmatologii i ortopedii

Vorobev A.V.
Nizhegorodskiy nauchno-issledovatelskiy institut travmatologii i ortopedii

Grishina A.A.
Nizhegorodskiy nauchno-issledovatelskiy institut travmatologii i ortopedii

Russkikh A.P.
Vyatskaya gosudarstvennaya selskokhozyaystvennaya akademiya


Abstract
Crystallostasis, a new parameter of homeostasis, has been proposed and validated on the basis of long-term investigations of crystallization pattern of various biological substrates in humans and animals and a critical analysis of the current state of the problem. Crystallostasis is treated as an ability of a biological system to keep its own crystallogenic potential at a constant level. General concept of crystallostasis, physiological crystallokinesis and its disorders (crystal pathology or crystal deposition diseases) has been formulated. Crystal pathology is considered as a systemic, spontaneously uncorrectable disorder of adaptive regulatory mechanisms that normally maintain organism biosystems in a native aggregate state. Some general approaches have been proposed to crystallotropic therapy (crystallotherapy) as a specific correction of crystal pathology.

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