Вестник Нижегородского университета им. Н.И. Лобачевского. Серия: Социальные науки

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Title of Article

PARTICIPATION OF SOLUBLE MAJOR HISTOCOMPATIBILITY CLASS I MOLECULES IN THE DEVELOPMENT OF CHRONIC OBSTRUCTIVE PULMONARY DESEASE

Issue	2
Date	2010

Article type	scientific article	UDC	616-092
Pages	541-543	Keywords	immunity, soluble major histocompatibility class I molecules, chronic obstructive pulmonary disease

Authors

Kubysheva N.I.Nizhegorodskiy gosuniversitet im. N.I. Lobachevskogo
Postnikova L.B.Nizhegorodskiy gosuniversitet im. N.I. Lobachevskogo
Presnyakova N.B.Nizhegorodskiy NII epidemiologii i mikrobiologii im. akad. I.N. Blokhinoy
Novikov V.V.Nizhegorodskiy gosuniversitet im. N.I. Lobachevskogo, Nizhegorodskiy NII epidemiologii i mikrobiologii im. akad. I.N. Blokhinoy

Abstract

We investigated the content of soluble major histocompatibility class I molecules (sHLA-I) and the level HLA-I+ of mononuclear cells in patients with chronic obstructive pulmonary disease in various biological media. As the chronic obstructive pulmonary disease progresses, the sHLA-I level in the blood serum, induced phlegm and expired air condensate increases against the background of the decrease in HLA-I+ blood mononuclear cells.

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