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Title of Article

Fas mRNA ALTERNATIVE SPLICING IN COLORECTAL CANCER TUMOR CELLS


Issue
2
Date
2010

Article type
scientific article
UDC
571.27
Pages
580-584
Keywords
Fas molecule, alternative mRNA splicing, colorectal cancer


Authors
Sakharnov N.A.
Nizhegorodskiy gosuniversitet im. N.I. Lobachevskogo

Novikov D.V.
Nizhegorodskiy gosuniversitet im. N.I. Lobachevskogo

Alyasova A.V.
Nizhegorodskaya gosudarstvennaya meditsinskaya akademiya

Novikov V.V.
Nizhegorodskiy gosuniversitet im. N.I. Lobachevskogo


Abstract
Seven alternative forms and 15 different spectra of Fas mRNA molecule have been revealed in the tumor cells of colorectal cancer patients. Tumor cells of colorectal cancer stage III patients have not shown the presence of Fas mRNA molecule with the deletion of exon 5, and in those of stage IV patients, Fas mRNA molecule with the deletion of exon 4 has not been detected .

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