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Title of Article

ASSESSMENT OF TUMOR IMMUNITY IN THE BODY OF THE UTERUS


Issue
2
Date
 2010

Article type
 scientific article
UDC
571.27; 616 - 006.5; 616 - 006.6; 618.14
Pages
653-658
Keywords
soluble differentiation antigens, oligomeric soluble differentiation antigens, cytokines, uterine myoma, endometrial cancer


Authors
Korovushkina K.A.
Nizhegorodskaya gosudarstvennaya meditsinskaya akademiya

Kotelnikova T.V.
Nizhegorodskaya gosudarstvennaya meditsinskaya akademiya

Kontorschikova E.Yu.
Nizhegorodskaya gosudarstvennaya meditsinskaya akademiya

Knyazev D.I.
Nizhegorodskiy gosuniversitet im. N.I. Lobachevskogo

Novikov D.V.
Nizhegorodskiy gosuniversitet im. N.I. Lobachevskogo

Presnyakova N.B.
Nizhegorodskiy NII epidemiologii i mikrobiologii im. N.I. Blokhinoy

Baryshnikov A.Yu.
Rossiyskiy onkologicheskiy nauchnyy tsentr im. N.N. Blokhina RAMN, Moskva

Novikov V.V.
Nizhegorodskiy gosuniversitet im. N.I. Lobachevskogo


Abstract
Endometrial cancer patients had higher serum concentrations of IL-10 and adhesion molecule soluble complexes CD18-CD54. The content of CD8+, CD25+, CD38+ and CD54+ mononuclear cells, IL-12, IFN-?, soluble CD8 molecules, oligolmeric CD50 molecules and soluble CD54 molecules were elevated in endometrial cancer as well as in uterine myoma. Only uterine myoma patients had higher levels of CD18+ and CD50+ mononuclear cells.

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