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Title of Article

THE EFFECT OF ETHANOL, HEPARIN AND PROTAMINE SULFATE ON THE ACTIVITY OF ALANINE AND ASPARTATE AMINOTRANSFERASE


Issue
2
Date
2011

Section
BIOLOGY

Article type
scientific article
UDC
612.57
Pages
98-101
Keywords
heparin, ethanol, protamine sulfate, alanine and aspartate aminotransferase


Authors
Krylov Vasiliy Nikolaevich
Nizhegorodskiy gosuniversitet im. N.I. Lobachevskogo

Malinovskaya Svetlana Lvovna
Nizhegorodskaya gosudarstvennaya meditsinskaya akademiya

Slobodyanyuk Vladimir Sergeevich
Nizhegorodskiy gosuniversitet im. N.I. Lobachevskogo

Malinovskiy Dmitriy Sergeevich
Nizhegorodskiy gosuniversitet im. N.I. Lobachevskogo


Abstract
It has been shown in the experiments on laboratory rats that ethanol (12%, 0.5 ml/rat) and 1000-5000 IU/kg heparin dose increase the activity of ALT and AST. When ethanol is introduced on the background of heparin injec-tion, the ALT and AST activities depend on the preliminary injected heparin dose. With the heparin dose of 2500 IU/kg, ALT and AST activities do not differ from the control values.

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