Главная страница
russian   english
16+
<< back

Title of Article

FLUORESCENCE SCANNING MONITORING OF CALCIUM ACTIVITY IN HIPPOCAMPAL NEURONS UNDER THE INFLUENCE OF SYNAPTIC TRANSMISSION MODULATORS


Issue
5
Date
2011

Article type
scientific article
UDC
535.33+57.086.8:577.175.82
Pages
146-151
Keywords
laser scanning microscopy, fluorescence analysis, neuron, neurotransmitter, purinergic receptors


Authors
Zakharov Yuriy Nikolaevich
Nizhegorodskiy gosuniversitet im. N.I. Lobachevskogo

Ershova Anastasiya Vasilevna
Nizhegorodskiy gosuniversitet im. N.I. Lobachevskogo

Kalintseva Yaroslava Igorevna
Nizhegorodskiy gosuniversitet im. N.I. Lobachevskogo

Mukhina Irina Vasilevna
Nizhegorodskiy gosuniversitet im. N.I. Lobachevskogo


Abstract
The problem of calcium activity mechanisms in neuronal tissue is considered using fluorescence analysis with application of neurotransmitters and blockers of postsynaptic receptors. Parameters of fluorescence dynamics in long-term signal recording have been optimized to interpret adequately the results of the neuronal activity studies. The leading role of chemical mechanisms to trigger neuron calcium cascades has been shown.

File (in Russian)