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Title of Article

LEVELS OF SOLUBLE DIFFERENTIATION MOLECULES OF IMMUNE SYSTEM CELLS IN CHILDREN'S SERUM


Issue
2
Date
2011

Article type
scientific article
UDC
612.014.1
Pages
98-102
Keywords
soluble differentiation molecules of immune system cells, total and oligomeric fractions of sCD25, sCD38, sCD95 and sHLA-DR


Authors
Pasheva Lyubov Aleksandrovna
Nizhegorodskiy gosuniversitet im. N.I. Lobachevskogo

Presnyakova Natalya Borisovna
Nizhegorodskiy NII epidemiologii i mikrobiologii im. I.N. Blokhinoy

Karaulov Aleksandr Viktorovich
Moskovskaya meditsinskaya akademiya im. I.M. Sechenova

Novikov Viktor Vladimirovich
Nizhegorodskiy gosuniversitet im. N.I. Lobachevskogo, Nizhegorodskiy NII epidemiologii i mikrobiologii im. I.N. Blokhinoy


Abstract
A comparative analysis has been carried out of the average level of total and oligomeric fractions of molecules sCD25, sCD38, sCD95 and sHLA-DR in the serum of different children aged from 3 to 17 years and adults. The analysis was performed by the sandwich ELISA method using monoclonal antibodies of the ICO series. The children's level of membrane protein soluble forms of immune system cells has been shown to differ in most cases from that of adults. Moreover, it is different in early and late childhood.

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