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Title of Article

SYNTHESIS OF CATIONIC BORONATED PORPHYRINS BY MODIFICATION OF AMINO GROUP OF 5-(4’-AMINOPHENYL)-10,15,20-TRIPHENYLPORPHYRIN


Issue
1
Date
2013

Article type
scientific article
UDC
41.244; 574.963; 541.49; 542.422.
Pages
118-123
Keywords
carboranes, porphyrins, 1,2,3-triazoles, 1,3-dipolar cycloaddition, boron neutron capture therapy (BNCT), photodynamic therapy (PDT).


Authors
Olshevskaya Valentina Antonovna
Institut elementoorganicheskikh soedineniy im. A.N. Nesmeyanova RAN, Moskva

Korotkova Natalya Sergeevna
Moskovskiy gosuniversitet tonkikh khimicheskikh tekhnologiy im. M.V. Lomonosova

Makarenkov Anton Vadimovich
Institut elementoorganicheskikh soedineniy im. A.N. Nesmeyanova RAN, Moskva

Luzgina Valentina Nikolaevna
Moskovskiy gosuniversitet tonkikh khimicheskikh tekhnologiy im. M.V. Lomonosova

Kalinin Valeriy Nikolaevich
Institut elementoorganicheskikh soedineniy im. A.N. Nesmeyanova RAN, Moskva


Abstract
Some previously unknown carborane-containing porphyrins including cationic ones have been synthesized by modification of the amino group of 5-(4’-aminophenyl)-10,15,20-triphenylporphyrin. All compounds obtained are promising agents for the BNCT and PDT of tumors and cationic carboranylporphyrins can be considered as precursors of DNA-binding ligands.

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