SYNTHESIS OF CATIONIC BORONATED PORPHYRINS BY MODIFICATION OF AMINO GROUP OF 5-(4’-AMINOPHENYL)-10,15,20-TRIPHENYLPORPHYRIN |
1 | |
2013 |
scientific article | 41.244; 574.963; 541.49; 542.422. | ||
118-123 | carboranes, porphyrins, 1,2,3-triazoles, 1,3-dipolar cycloaddition, boron neutron capture therapy (BNCT), photodynamic therapy (PDT). |
Some previously unknown carborane-containing porphyrins including cationic ones have been synthesized by modification of the amino group of 5-(4’-aminophenyl)-10,15,20-triphenylporphyrin. All compounds obtained are promising agents for the BNCT and PDT of tumors and cationic carboranylporphyrins can be considered as precursors of DNA-binding ligands. |
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