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Title of Article

EFFECTS OF SUCCESSIVE EXPOSURE TO GAMMA RADIATION AND LOW-INTENSITY RED LIGHT ON RAT MUSCLE TISSUES


Issue
2
Date
2013

Section
BIOLOGY

Article type
scientific article
UDC
612.73/.74-074:612.014.48
Pages
113-117
Keywords
free radical oxidation, ionizing radiation, red light, ultrastructure of skeletal muscles


Authors
Bavrina Anna Petrovna
Nizhegorodskaya gosudarstvennaya meditsinskaya akademiya

Monich Viktor Anatolevich
Nizhegorodskaya gosudarstvennaya meditsinskaya akademiya

Malinovskaya Svetlana Lvovna
Nizhegorodskaya gosudarstvennaya meditsinskaya akademiya

Yakovleva Evgeniya Ivanovna
Nizhegorodskaya gosudarstvennaya meditsinskaya akademiya

Bugrova Marina Leonidovna
Nizhegorodskaya gosudarstvennaya meditsinskaya akademiya

Ermolaev Vladimir Sergeevich
Nizhegorodskiy oblastnoy onkologicheskiy dispanser

Druzhinin Evgeniy Aleksandrovich
Nizhegorodskiy oblastnoy onkologicheskiy dispanser


Abstract
We consider the peculiarities of free radical oxidation in the skeletal muscle tissues of rats after their successive exposure to gamma-rays and to low-intensity broadband red light. A reduction in the level of protein oxidative modification products in the light-treated samples has been revealed. The changes in peroxidation activity are accompanied with the ultrastructure alteration of striated muscle fibers in the samples treated with light as compared to the control group samples. On the basis of the results obtained, it has been concluded that low-intensity broadband red light may have a radioprotective effect and can be used to correct the damage caused by ionizing radiation.

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