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Title of Article

M-CHOLINOBLOCKER ACTIVITY OF HUMAN BLOOD SERUM IN THE EXPERIMENTS WITH PORCINE CORONARY ARTERY RING SEGMENTS


Issue
 
Date

Article type
 scientific article
UDC
612.73+612.118.2+612.172.1+612.181.5
Pages
133-139
Keywords
 


Authors
R§SѓR»RєReRЅR° R•.Rђ.
R’SЏS‚SЃRєReR№ RіRѕSЃSѓRґR°SЂSЃS‚RІRµRЅRЅS‹R№ RіSѓRјR°RЅReS‚R°SЂRЅS‹R№ SѓRЅReRІRµSЂSЃReS‚RµS‚, RљReSЂRѕRІ; RљReSЂRѕRІSЃRєR°SЏ RіRѕSЃSѓRґR°SЂSЃS‚RІRµRЅRЅR°SЏ RјRµRґReS†ReRЅSЃRєR°SЏ R°RєR°RґRµRјReSЏ

R“SѓR»SЏRµRІR° RЎ.R¤.
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R¦ReSЂRєReRЅ R’.R?.
RљR°R·R°RЅSЃRєReR№ RіRѕSЃSѓRґR°SЂSЃS‚RІRµRЅRЅS‹R№ RјRµRґReS†ReRЅSЃRєReR№ SѓRЅReRІRµSЂSЃReS‚RµS‚

RљRѕSЃS‚SЏRµRІ Rђ.Rђ.
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Abstract
10-, 50-, 100-, 500-, and 1000-fold dilutions of venous serum of healthy women, healthy men and men with coronary heart disease were studied in the experiments with 195 ring segments of the porcine right coronary artery. Human serum provides M-cholineblocking activity that can be explained by the presence of an endogenous non-selective M-cholinoreceptor blocker whose content depends on the gender and the presence of coronary heart disease.

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