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Title of Article

THE EFFECT OF ERYTHROCYTE MICROVESICLES ON THE FINAL STAGE OF BLOOD COAGULATION


Issue
1
Date
2014

Article type
scientific article
UDC
616.151.5-072.7
Pages
233-236
Keywords
microvesicles, plasma coagulation, erythrocytes, platelet aggregation


Authors
Sukhareva E.G.
Nizhegorodskiy gosuniversitet im. N.I. Lobachevskogo; Nizhegorodskiy NII travmatologii i ortopedii

Levin G.Ya.
Nizhegorodskiy NII travmatologii i ortopedii


Abstract
In this paper, we present the results of our investigation of the effect of erythrocyte microvesicles isolated after incubating unwashed red blood cells from healthy donors with anticoagulant for 7 days. Erythrocyte microvesicles are shown to have not only pro-aggregation, but also pronounced procoagulant action on the final stage of blood coagulation. We have also found out that Erythrocyte microvesicles enhance spontaneous aggregation of platelets and fibrin formation.

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